Healthcare ETF Overview

With 44 ETFs traded in the U.S. markets, Healthcare ETFs gather total assets under management of $54.78B. The average expense ratio is 0.59%. Healthcare ETFs can be found in the following asset classes:

  • Equity

The largest Healthcare ETF is the Health Care Select Sector SPDR Fund XLV with $17.46B in assets. In the last trailing year, the best performing Healthcare ETF was the LABU at 125.76%. The most-recent ETF launched in the Healthcare space was the Direxion Daily Pharmaceutical & Medical Bull 3X Shares PILL in 11/15/17.


LABUDirexion Daily S&P Biotech Bull 3X Shares22.13%
PILLDirexion Daily Pharmaceutical & Medical Bull 3X Shares17.98%
CUREDirexion Daily Healthcare Bull 3x Shares15.80%
UBIOProShares UltraPro Nasdaq Biotechnology13.61%
BBCVirtus LifeSci Biotech Clinical Trials ETF12.81%


LABDDirexion Daily S&P Biotech Bear 3X Shares-21.81%
ZBIOProShares UltraPro Short Nasdaq Biotechnology-13.82%
RXDProShares UltraShort Health Care-9.27%
BISProShares UltraShort Nasdaq Biotechnology-9.08%
DXJHWisdomTree Japan Hedged Health Care Fund0.94%

top creations

XHESPDR S&P Health Care Equipment ETF22.76
IXJiShares Global Healthcare ETF22.66
FHLCFidelity MSCI Health Care Index ETF16.05
PSCHPowerShares S&P SmallCap Health Care Portfolio14.72

top redemptions

XLVHealth Care Select Sector SPDR Fund-717.30
IYHiShares U.S. Healthcare ETF-149.41
LABUDirexion Daily S&P Biotech Bull 3X Shares-88.98
VHTVanguard Health Care ETF-69.78
IBBiShares NASDAQ Biotechnology ETF-38.49


RXDProShares UltraShort Health Care65.75%
ARKGARK Genomic Revolution Multi-Sector ETF15.68%
ZBIOProShares UltraPro Short Nasdaq Biotechnology15.00%
LABUDirexion Daily S&P Biotech Bull 3X Shares14.50%
HCRFiShares Edge MSCI Multifactor Healthcare ETF13.68%


IHFiShares U.S. Healthcare Providers ETF-14.14%
LABDDirexion Daily S&P Biotech Bear 3X Shares-9.42%
BIBProShares Ultra NASDAQ Biotechnology-7.95%
PJPPowerShares Dynamic Pharmaceuticals Portfolio-7.54%
PBEPowerShares Dynamic Biotechnology & Genome Portfolio-7.29%

ETF Report

 Sectors In Review

Across the board, sectors were generally up in November

Daily ETF Watch

First Pot ETF In US Starts Trading

Rollout was a bit of a late Christmas gift for fans of the growing cannabis industry, but it may not be what they think.

Features and News

Tax Reform’s Impact On ETFs, Economy

Republican tax bill likely to be signed into law by end of the year. 

ETF Report

Hidden Gem ETFs

The greatest ETFs you've never heard of.

Features and News

What To Know About Sector ETF Investing

With sectors, Fidelity's Denise Chisholm says the key is understanding how different cycles perform over time.

Daily ETF Watch

Direxion Debuts Pharma ETF Revamp

New 3X fund offers leveraged smart-beta exposure to the pharma space.

Daily ETF Watch

KraneShares Plans 2 Unique Funds

Firm known for its China ETFs takes on electric cars and emerging market health care.

Features and News

Top Performing ETFs Of All Time

Gains for these ETFs range from 800% to more than 3,000%.

Features and News

Earnings Not Sole Driver Of Stock ETFs Rally

Earnings are rising, but not as fast as the stock market. There’s more at play.