Pfizer Inc. is a company in the U.S. stock market and it is a holding in 227 U.S.-traded ETFs. PFE has around 396.4M shares in the U.S. ETF market. The largest ETF holder of PFE is the SPDR S&P 500 ETF Trust (SPY), with approximately 63.77M shares. Investors may also find of interest that the ETF with the largest allocation to PFE stock is First Trust Nasdaq Pharmaceuticals ETF (FTXH), with a portfolio weight of 7.95%. On average, U.S. ETFs allocate 1.29% of PFE to their portfolios.

Additionally, PFE is a favorite stock for Vanilla and Multi-factor ETFs. It is also most likely to belong to Broad-based ETFs. The best-performing ETF in the past 12 months with PFE as a holding is the ProShares UltraPro S&P500 (UPRO), with a return of 70.99%.