Top 5 ETFs Positioned to Benefit From the AI Power Demand Boom

The AI-driven power demand theme isn’t theoretical, it’s already translating into real earnings momentum.

ETF.com
Apr 22, 2026
Edited by: ETF.com Staff
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GE Vernova (GEV), one of the key suppliers of power equipment and grid infrastructure, just delivered a breakout quarter that underscores how quickly AI is reshaping the energy landscape.

Artificial intelligence is an energy story.

As hyperscale data centers expand globally, the electricity required to power AI workloads is surging. That shift is creating a powerful second-order investment theme: the infrastructure behind AI power generation, electrification and grid modernization.

For investors looking beyond semiconductors, a growing group of ETFs offers exposure to the companies enabling this transformation.

Below are five ETFs positioned to benefit from the AI-driven power demand boom.

ETF Snapshot: AI Power Demand Beneficiaries

ETFTickerFocus AreaExpense Ratio
Defiance AI & Power Infrastructure ETFAIPOAI + power infrastructure0.69%
Utilities Select Sector SPDR FundXLUU.S. utilities0.08%
Global X Uranium ETFURANuclear energy0.69%
First Trust Clean Edge Smart Grid Infrastructure ETFGRIDGrid + electrification0.56%
ALPS Clean Energy ETFACESRenewable energy0.55%

Performance Snapshot
 

ETFTickerYTD Return1-Year3-Year Annualized
Defiance AI & Power Infrastructure ETFAIPO31.19%N/A (New Fund)N/A (New Fund)
Utilities Select Sector SPDR FundXLU6.02%21.74%12.27%
Global X Uranium ETFURA25.77%151.03%47.47%
First Trust Clean Edge Smart Grid Infrastructure ETFGRID18.16%65.24%24.29%
ALPS Clean Energy ETFACES6.69%63.99%-6.59%

Defiance AI & Power Infrastructure ETF (AIPO)

Best pure-play AI power infrastructure ETF

AIPO ETF is one of the most targeted ways to invest in the intersection of AI and energy.

The fund focuses on companies tied to:

  • Electrical infrastructure
  • Power generation
  • Data center energy systems

As AI scales, the constraint is increasingly electricity. AIPO is built to capture that shift directly.
 

Utilities Select Sector SPDR Fund (XLU)

Best broad utility exposure

XLU ETF provides exposure to large U.S. utilities, many of which are becoming critical partners to hyperscale data centers.
 

Key tailwinds:
 

  • Long-term power purchase agreements with tech firms
  • Rising baseload demand
  • Accelerating grid investment

For investors seeking lower volatility and income, XLU offers a more defensive way to play AI’s power needs.


Global X Uranium ETF (URA)

Best nuclear energy play

URA ETF provides exposure to uranium miners and nuclear fuel supply chains.

Nuclear energy is gaining renewed attention because it offers:

  • 24/7 baseload power
  • Carbon-free generation
  • Scalability for AI data centers

As AI demand accelerates, nuclear is increasingly viewed as a critical long-term solution.
 

First Trust Clean Edge Smart Grid Infrastructure ETF (GRID)

Best grid modernization ETF

GRID ETF focuses on the transmission and distribution side of the equation.

AI growth requires not just more power—but better delivery systems

The fund includes companies involved in:
 

  • Smart grid technology
  • Grid equipment and components
  • Electrification infrastructure

This makes it a direct beneficiary of rising capital expenditures across global power networks.
 

ALPS Clean Energy ETF (ACES)

Best clean energy + AI convergence play

ACES ETF offers exposure to renewable energy companies increasingly tied to data center growth.

Hyperscalers are prioritizing:

  • Carbon-neutral AI operations
  • Co-located renewable energy
  • Battery storage integration

This trend is helping support demand across the clean energy ecosystem.

The Bigger Theme: AI’s Infrastructure Trade

The first phase of AI investing centered on semiconductors and cloud computing.

The next phase is about powering that intelligence.

We’re seeing a shift toward:

  • Utilities as long-term AI enablers
  • Nuclear as a baseload solution
  • Grid infrastructure as a bottleneck
  • Renewables as a sustainability layer

Together, these trends form what could be the next major leg of AI-driven investing.

AI doesn’t scale without electricity.

These ETFs provide diversified exposure across the ecosystem required to power the next generation of technology:
 

  • AIPO – targeted AI + power infrastructure
  • XLU – utilities and stable power demand
  • URA – nuclear energy exposure
  • GRID – grid modernization
  • ACES – clean energy integration

As AI adoption accelerates, the race to build and supply power infrastructure may become one of the most important.
 


This article was generated with the assistance of artificial intelligence and reviewed by ETF.com staff.

Top 5 ETFs Positioned to Benefit From the AI Power Demand Boom
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